Biostimulator is poly-L-lactic acid (PLLA) — it doesn't fill space directly. Instead, it stimulates your own collagen production gradually over weeks to months. Results build slowly (you won't see the full effect for 6-8 weeks, sometimes longer) but last up to 2+ years. It's ideal for overall facial volume loss, "global" rejuvenation, and treating larger areas like cheeks, temples, and even body areas (buttocks, décolletage). Requires the 5-5-5 massage protocol post-injection and usually multiple sessions spaced a month apart.
Radiesse is calcium hydroxylapatite (CaHA) — it provides immediate volumizing/lifting on injection AND stimulates collagen over time, so you get a dual effect: instant correction plus a biostimulatory tail. Results last about 12-15 months. It's denser and better for more targeted structural correction — jawline definition, chin projection, cheekbone contour, and hand rejuvenation. Lower dilution = more lift; higher dilution (often used off-label, like "skin boosting" techniques) = more diffuse collagen stimulation.
